Realtors know that smart location is everything in buying or selling property. Try to sell a house that's near a busy highway or high tension wires, and you'll learn this. In story, a good location is also really important--I wouldn't say it's everything, but it's as vital as good characters and strong plot.
Unfortunately, it's the aspect of writing that many writers tack on or ignore altogether. Mostly due to impatience, I've learned. Or the belief that once you've described the weather and how a room looks, the reader can retain than for 300+ pages.
I don't know if the analogy really works, but I see smart location like a smart phone--it is where the reader taps in, to orient, to learn more, to feel the character's communication with her life.